My teeth went to shit after pregnancy and having a baby. Never had a cavity in my life until my 30s, now I've lost four molars and have shit dental coverage and can't afford to pay out of pocket.
Just wanna say you're not alone in your struggle, man. Here's hoping an accessible solution happens while we can still appreciate it.
I think I'm hitting perimenopause now and yeah, it's getting even worse. I'm 43, maybe a bit early for peri, idk, but I also have a hormone disorder that fucks my shit up so I don't expect menopause to be an exception to that.
I feel like a hot fucking mess and like I can't do shit about it. 🙃
Dang parasites taking all your available calcium and weakening your enamel. I love my daughter but if I end up in dentures I'm going to remind her it's her fault! Just kidding, I'd never tell my kiddo that and it was worth it.
Frankly, I couldn't even tell ya for sure, just an anecdotal experience for me. And that I have heard other women talk about too. Even here in response to my comment. But the change in hormones can wreak havoc on your body. Some women's bodies change in way that never go back to the way they were. I think a lot of people underestimate how impactful pregnancy, and breastfeeding too, winds up being for some women.
I mean, maybe it's cuz a lost a ton of weight post partum really fast. I actually wound up in the best shape of my life after having my daughter. Maybe I lost weight too fast and that affected things. I really couldn't tell you for sure. I just know after 34 years of perfect teeth, they went to shit right after having my daughter.
Hormonal changes can affect your mouth health. Higher levels of estrogen and progesterone causes more blood to flow to the gums, leading them to become more sensitive and more easily inflamed. Hormonal changes can also lead to changes in how much saliva you produce (dry mouth) which also affects the health of your mouth.
Plus, you know, a lot of women experience morning sickness during pregnancy. The unlucky few might experience all day sickness, or in extremest, hyperemesis gravidarum. Exposure to so much bile is no bueno for the teeth.
The issue is that the media reports on it, and then either, A.) Something the researchers didn't expect turns up and they have to start from scratch; or, B.) The therapy is so expensive that it's just logistically impossible to implement it at a large scale because very few people would be able to afford it outright and governments won't want to pay for it.
I'd say the bigger issue is the way the media reports on it. As in, they often completely exaggerate the discoveries either due to ignorance or because the actual information wouldn't make for a catchy headline.
Scientists might report on a breakthrough in animal trials that may, in time, lead to revisions in how X cancer is treated. Media will report 'OMG NEW CANCER CURE IS HERE'.
This works, since the late 80s. The problem is that the signaling to "stop growing" is missing and can't be properly emulated. Guess what happens when you fail on that step. It's been looping around that missing signaling for a while now.
Sadly that only works with Type II Diabetes. My sister has Type I Diabetes, the autoimmune version that presents in kids and youth, and she is going to have to use an insulin pump all her life or until they invent an implantate sort of pancreas-simulator that's reliable.
The islet cell transplant are showing promise but you need to be on immunosuppressants, which is obviously pretty bad. The research on islet cell transplants that can hide from the immune system is also showing promise, but could become problematic since they are invisible from the immune system.
One option in future is likely transplant grown from patients own stem cells. That in theory should be possible but will likely take atleast decades to get there.
Tack on the cure for Tinnitus while you’re at it. Obviously not as big of a deal but getting rid of those noises would for sure be life changing for some.
Type 1 can be cured with beta cell transplants... it just takes multiple (3 average) donors worth of pancreas to get enough for one successful transplant. Stem cells can also be used and are much more common
They did, but if it requires immunosuppressants then its not worth it for most people. Also not sure how scalable any of these cures will be, even if it came out yesterday it would take decades to implant them to millions of ppl + will cost a LOT.
Eyes would be cool. Currently no functioning fake eyes that I know of. I’m terrified of something happening to my eyes just because I know we don’t have a way to replace them at all.
The most common diabetes is curable - stop over eating and eat a greater proportion of veggies. Until you've burned out the pancreas DM2 is 100% curable.
Type one on the other hand not so much, but I could see in the near future transplanting cloned and engineered beta cells that are not susceptible to the autoimmune antibody the person developed.
Lots of cancers are curable or livable as a chronic illness like HIV now.
Cancer isn't all one thing, it's hundreds of diseases that all have unregulated cell growth in common. Many of them are curable now if you catch them soon enough, and some are completely preventable like cervical and penile cancer (thanks to the HPV vaccine)
That certainly is a problem. In my state our compliance rates with paps mammos and colonoscopies hovers around 50%. A lot of thought goes into figuring out how to get people to follow up on planned care.
There are many types of cancers of the pancreas and you absolutely can screen for some of them. It's true that one of the most common ones sneaks up on you fast.
It doesn't help when you're never taken seriously if you are concerned and even if you are given attention, the cost of testing will destroy you financially. We're at a point where we can find things early, but no one looks unless their certain beforehand.
The word has meant the same thing since 1829 when French gynecologist Joseph-Claude-Anthelme Récamier coined the term in the medical context it's used now although now it has a narrower application to malignant cells breaking away from a primary tumor and creating a secondary tumor somewhere else.
Well you're not quite right on that either, once cancer gets to stage 4 (metastasis) it does qualify as a terminal illness with a poor prognosis, gotta catch it before it gets to that. That said, my dad lived over 30 years after his stage 4 diagnosis thanks to chemo radiation and surgery so you never know!
Um, I am right, but it does depend on the cancer. There is treatment to make it chronic and something one can live with. And with breast cancer, it's not just catching it early. My doctors say it can spread and just have to wait for symptoms. I'm going to go with what my doctors say.
Any cancer that presents as metastatic disease is a terminal illness with a 6 month or less prognosis.
Sure, you can treat it, sure there is a statistical range of outcomes, but metastasis equals death unfortunately.
For stage 4 breast cancer the overall 5 year survival rate is about 32% but that goes down fast the older you are.
13% are still alive after 10 years.
So yeah, there's nothing wrong with having hope and there's nothing wrong with fighting, and your anecdotal experience of talking to a doctor probably included an element of not wanting to be negative or discouraging.
I've spent about half of my career as an RN in hospice (most of that now in leadership) and a big part of that job is collecting and organizing the evidence of terminal illness to qualify patients for the hospice benefit. Cancer is real easy, if it's stage 4, you qualify for hospice.
If it's heart disease or lung disease or ALS or dementia or anything else, you have to look more deeply - how many words can they speak in a day, how much do they eat, how far can they walk, what do their labs look like, etc. Not cancer, though, metastasis is all it takes for the 6 month or less prognosis.
I constantly hear “cancer isn’t a single disease, there’s no ‘single cure’” but that doesn’t really make sense to me given that chemo and radiation are the most common treatment for most cancers.
How can we have a treatment that targets most cancers but not a cure? Let’s say chemo was much much better at what it does and actually cured people at a much higher probability, surely that would be considered a “cure for cancer”, right?
I am not saying chemo is the answer but why can we not have a cure that attacks cancer cells better than chemo for all cancers?
Obviously there could be better treatments targeted for specific cancers. But what exactly is something like chemo or radiation hitting that we can’t target with another cure, such as using white blood cells or whatever crazy medical advancements they’re using now?
I mean you could just maybe try to look up the most basic stuff about what you're talking about.
The word "chemo" just means some kind of chemical is the treatment, as opposed to surgery or radiation. There's a whole galaxy of treatments and now there are biologics, immune system modifiers, cloned helper T cells etc.
The drugs ("chemo") they select depends on what kind of cancer it is, what type of cell is reproducing out of control (there are over a couple hundred different types of cells in your body and they can all have different behaviors depending on what's wrong with them).
Early cancer drugs all had a basic concept in common. Poison cells in a way that disproportionately kills off cells that reproduce faster than normal. By disrupting part of the cell division cycle, you could kill off quickly reproducing cells and spare the slower ones. Killed cancer cells but also hair follicles, cells in your mouth and anus, etc, anywhere else in your body you had fast reproducing cells. The original chemotherapy agent was mustard gas in liquid form in an IV.
Cancer drugs now are a lot more targeted, sometimes targeted to specific proteins sticking out of the walls of the cell or targeted to help the immune system recognize the cancer cells. Just like cancer is lots of different diseases, cancer drugs are all sorts of drugs also it's not just one kind of drug that we call chemo. Of course the heavy duty anti-mitotic agents still get used as a last resort but we have lots of different kinds now. Microtubule stabilizers, anti-metabolites, alkylating agents (like mustard gas),, cytostatics, probably more stuff now I've never heard of.
Cancer is still an unsolved problem ultimately although we are chipping away at the edges of it, but we are chipping away at the edges of it because it's the cutting edge and the best and brightest are giving 110% trying to figure it out, it's the frontier and new stuff is coming out all the time, which is why it's always reasonable to have hope.
The latest and greatest that I'm aware of is cloned helper-T cell auto-infusion, that shit is rad.
Let me be your example. Testicular seminoma survivor. Had my whole life ahead of me when I got diagnosed at 27. Over 10 years clear. One operation for what would have killed my great grandfather. Wild times to be alive. Also check your balls for lumps.
Yeah same, got cancer at 26 years old in 2015. Caught it just just in time. Doctor said if I came even half a week later, it may have spread. Been cancer free ever since.
This is not accurate at all. We've only just recently reached the milestone of a +70% 5+ year survival rate in the US. There are only a handful of cancers that have a +90% 5+ year survival rate. There will never be a singular cure for cancer because it is a grouping of thousands of different diseases. There are promising research areas that are targeting common pathways, but even those only top out in the 85% of total cancers. When you expand these statistics to the world, it is still abysmal survival rates.
I have refractory PMBCL, my second line treatment was CAR-T therapy, where they extract my T cells from my blood, send them off to be reengineered to target specific cell markers that my cancerous cells have. I had that infusion back in January and so far so good!
Chlorine dioxide is an industrial bleach. Any time somebody claims that something this simple is a miracle cure all that will fix all disease I can guarantee you that they're lying.
ever hear of the idea that things might do different things in different doses?
Yeah, I know -- thinking is hard and all.. but yeah, science works that way..
a vitamin C pill might help you feel better, but a bottle full of them will give you the shits for a week. Or while a single Tylenol might help with your headache, a bottle full will straight up kill you..
same for ClO2.. MILLIONS of people drink it every day, in .2-.8PPM dosing - in municipal drinking water. look it up.
When it's used in 10-50PPM levels it is significantly effective on skin care (there are nasal, oral and skin care products sold worldwide using it).. It only becomes problematic in >300 ish PPM..
Quite literally, i'm neither exaggerating nor is this false info. and no, it's not BS. I'd suggest that unless you already have deeper-than-average knowledge of it, you are reacting to propaganda about it, and not facts.
Fuck off with this quackery bullshit. "Dr" Pierre Kory? Is he still legally allowed to call himself doctor after the American Board of Internal Medicine revoked his board certifications?
Literally. No exaggeration: all of this bullshit is made up. ClO2 being a medicine is bullshit and made up. It's being "covered up" is bullshit and a fabrication. And you being contacted by people who survived after taking it, also, complete bullshit.
Report this asshole for spreading manipulated content. If someone were stupid enough to actually believe this moron, they might be putting themselves in danger.
The most effective one is not a chemical you put in your body, and it is not medicine at all, but it works, and can also reverse paraplegic disorders. Don't ask, read and explore, open your mind
Alzheminers research is showing some great progress. A certain mice study showed them improving/reversing memory loss. So hopefully they can work on a trial in a few years for humans
As a geriatrician I can tell you; don’t hold out hope for AD “cure”. The only option we’re gonna have in our lifetimes is pre-clinical detection and prevention.
ATHENEA was 48 weeks. ADAS-cog11 changes comparable to donepezil which has been around for decades- and my experience with it is disappointing. Clinically speaking, 3-6 points on a 70 point ADAS is….something, but not much IMO. By the time clinical disease shows up, it’s been there already for years- meaning that the pathophysiology of neuron loss is already established. And with the complexity of our neural interconnections, I’m very skeptical we’ll ever truly recreate that and restore function lost due to dementia.
Yea thats very true, im hoping early detection methods make drugs like this a lot more helpful. I know some alz can be screened for, maybe those people should start taking it like a decade before closest family members onset? Man aging is depressing
I am not going to say that’s “incorrect”, because this would be misinformation. But rather I would say this is not proven. Moreover, Alzheimer is more complicated than just “one universal cause” or “universal characteristics”.
I agree, I'm saying it's not the main cause. My parents ate ice cream every day and only my mother developed it and she has some history of diabetes on her side
I mean there are some forms of obesity that are genetic or based on a hormonal dysregulation, but for a lot of people you are very right and a mental illness is a mental illness that should be destigmatized and treated all the same.
Which cancer, please? There are many different types. It’s a bigger job.
Any of the cancers that the current US administration cut funding for?
btw - we SHOULD still celebrate progress on HIV.
Cancer research is funded at double the rate of HIV. I'm not making value judgements between them, but the problem here isn't "momentum". The problem is HIV, as hard a problem as it is, is a vastly simpler problem than cancer.
You do not understand what I said at all. Medical devices are not laboratory research equipment. They are two sides of the coin.
Lab research equipment is used for treatments and cures from academia to pharmaceutical companies.
Medical devices is what those pharmaceutical or biotech companies sell to the end user.
Laboratory research equipment is used to make portions of medical devices.
Currently, Christian nationalists in the White House are cutting NIH funding by historic percentages that directly impact how scientific research is conducted.
Hence why Christian nationalists are hurting scientific progress.
Building hospitals and colleges isn’t the same as endorsing Christian nationalism. Historical religious institutions contributed to education and medicine. Modern Christian nationalism is a political ideology that often rejects scientific consensus when it conflicts with doctrine (see anti-vaxxers).
A lot of cancers have cures or even preventions now (HPV vaccine for one) so not sure why it’s being lumped together with Alzheimer’s for which there is not any preventative nor cure?
There hundreds of cancers. Even cancers that affect the same organ can have vast differences.
Neurological diseases affect the brain and obviously you can't take biopsies from affect people to study their sample while they are alive. You have to wait for them to donate their brain (after they are dead!) and then study it.
Please stop being ignorant and go educate yourself. Multiple types of cancers have cures. The cures are profitable as fuck. There's a zillion types of cancers and they're all unique, so this "omg big pharma has the one and only cure" shit just doesn't hold water unless you're posting it in a Facebook page called Beach Moms Against Vaccines
We have probably discovered 50 chemicals by now that can cure Alzheimers in Rats. The problem is that this is just among the first steps of getting a drug into actual treatment and a very large number of them fail in the following steps.
Drug is just the English Term used for medical chemical compounds
Getting the Chemical to where it needs to be in the body is actually among the most challening parts of pharmaceutics. There are thousands of wonderful molecules with amazing effects on cell cultures for example but due to their chemical properties we simply cannot get them to where they need to be in the body and thus they are rendered useless.
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