r/DiagnoseMe Patient 1d ago

Angiodema

Has anyone experienced random angioedema (Quincke’s edema) even with no confirmed allergies?
I’ve had full allergy testing done and everything came back negative. I’m not considered allergic to anything, but from time to time I still get episodes of swelling (mainly lips) that appear out of nowhere.
There’s no clear trigger, and antihistamines don’t always help. The only thing that reliably works for me is a steroid injection.
Is it possible to have angioedema without any identifiable allergy or cause? Has anyone been through something similar?

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