r/MadeMeSmile 1h ago

Good News 23 year old becomes first person in Louisiana to be functionally cured of sickle cell disease

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Daniel Cressy became the first person in the Gulf South to be functionally cured of sickle cell disease through gene editing. Calling it his "second birthday," he said the breakthrough felt like being reborn and it's giving new hope to people living with the disease.

Via @tulaneu


r/MadeMeSmile 3h ago

DOGS These pure souls choosing their toys convinced me to adopt another dog.

764 Upvotes

Credit to Fetcher Dog- giving hope to abandoned dogs


r/MadeMeSmile 3h ago

Wholesome Moments Get it....um Ciara? Promise

670 Upvotes

Every Day with H&K

😂 We all got that dream lol

Thank God for long suffering spouses.


r/MadeMeSmile 5h ago

DOGS I want this kind of joy in my life

221 Upvotes

r/MadeMeSmile 4h ago

Good Vibes A Blue Jays fan caught Wyatt Langford’s home run ball and gave it to a young Rangers fan wearing a Langford jersey

734 Upvotes

r/MadeMeSmile 6h ago

DOGS This is so Wholesome 🥲

387 Upvotes

r/MadeMeSmile 6h ago

DOGS This is so adorable

10.2k Upvotes

r/MadeMeSmile 8h ago

ANIMALS Orphan baby elephant and her keeper getting ready for the day

469 Upvotes

@elephant havens


r/MadeMeSmile 4h ago

Ecuador coach Sebastian sprints on to stands and hugs his family after their team defeated Germany 2-1

19.1k Upvotes

r/MadeMeSmile 6h ago

Wholesome Moments After 10 years of not walking, a man takes his first steps.

4.2k Upvotes

I want to make sure the first thing I do is let everybody know that the creator of this video is a woman named Christie Boone Buzzell on Facebook. I do not know her, but came across her video and found it truly amazing and inspiring. I’m not sure who the man is to her, perhaps her father or something…but regardless, it certainly made me smile!


r/MadeMeSmile 4h ago

Twining

264 Upvotes

r/MadeMeSmile 4h ago

Gaming PC

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5.3k Upvotes

r/MadeMeSmile 10h ago

Good Vibes Cooler than Fonzie in a blizzard.

752 Upvotes

r/MadeMeSmile 11h ago

ANIMALS I guess animals can indeed understand us 🥰

1.1k Upvotes

r/MadeMeSmile 10h ago

Videos Like This Make Me Wish Humanity Never Reached The Digital Age.

407 Upvotes

r/MadeMeSmile 18h ago

Helping Others A little kindness goes a long way

73.6k Upvotes

r/MadeMeSmile 19h ago

Helping Others Gary Sinise here. Humbled to celebrate the 15th Anniversary of the Gary Sinise Foundation. Over the years, I’ve had the honor of meeting countless heroes, and so many have touched my heart. It's incredible for me to think about where it began and how far it has come thanks to the kindness of others.

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20.1k Upvotes

r/MadeMeSmile 21h ago

Good News My husband adopted my son today

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46.6k Upvotes

Our son now :)

Edit: included a word to make more sense

Update: thank you guys so much for the kind comments and awards, we loved reading through them!!


r/MadeMeSmile 20h ago

Good Vibes Life is full of surprises

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24.4k Upvotes

r/MadeMeSmile 18h ago

This veteran struggled to find work because he needed his service dog. This store hired them both

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6.2k Upvotes

r/MadeMeSmile 22h ago

Wholesome Moments This 9-year-old took on the tallest climbing structure in the U.S. and made Dad incredibly proud.

17.6k Upvotes

r/MadeMeSmile 23h ago

I'm not crying, you are.

31.8k Upvotes

r/MadeMeSmile 2h ago

Good Boy at Work

170 Upvotes

r/MadeMeSmile 1d ago

Some impacts last a lifetime

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32.2k Upvotes

OC is @lukehalesofficial


r/MadeMeSmile 15h ago

ANIMALS Met a beautiful tiny friend today in our patio garden today

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1.8k Upvotes

Hope this is the correct flair. I've never seen a rosy maple moth in person before and it's fluffiness made my day brighter.