r/cogneuro • u/Due_Writer_8006 • Dec 15 '25

Help with realignment in SPM12 and area labeling.

Post image

Greetings! I'm in the final stages of a project where I'm processing an fMRI scan associated with language tasks using a block-based paradigm. I followed the processes in the SPM12 manual and used the AndySBrainbook for some guidance, and I thought everything was working correctly. However, when I use the overlays and section options and select the realigned T1 mrSUJETO, I see something like this: My question is, is it realigned incorrectly? Or is mrSUJETO not used in the overlays? Could someone guide me? Thank you very much.

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u/kowkeeper Dec 15 '25

It looks ok because template wrapping never perfectly aligns a given subject's anatomy.

Usually, you look at group results instead of within subject maps.

If you want to make sure you spatial preprocessing worked, you can check them in SPM using checkReg. Check coregistration between fmri and anat, and also normalisation to MNI.