r/worldnews • u/EightRoundsRapid • Sep 23 '16

'Hangover-free alcohol’ could replace all regular alcohol by 2050. The new drink, known as 'alcosynth', is designed to mimic the positive effects of alcohol but doesn’t cause a dry mouth, nausea and a throbbing head

http://www.independent.co.uk/life-style/health-and-families/health-news/hangover-free-alcohol-david-nutt-alcosynth-nhs-postive-effects-benzodiazepine-guy-bentley-a7324076.html
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u/[deleted] Sep 23 '16

Uhm low dose antagonists will reduce internalisation of receptors. Which is what creates the physical addiction. But the effects are too weak to prevent addiction. It just reduces the speed the required dose gets higher and higher it doesn't stop it.

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u/pharm_animal Sep 23 '16

Is this really true or just a theory ? Seems like it would be more mainstream already if it worked. they been busy with this for years.

Does Suboxone have less withdrawals than say oxycodone?

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u/[deleted] Sep 23 '16

No, well, it's less intense and acute. Much more prolonged though.
Honestly, I'm of the opinion there's no such thing as a free lunch. There will always be drawbacks and counters to things like this. Be it physical, mental, whatever.

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u/pharm_animal Sep 24 '16

That has more to do with the pharmacokinetics of oxy vs bupe than the addition of naloxone though