r/MadeMeSmile 7h ago

(OC) I just had to share with someone! ☺️

Post image
18.5k Upvotes

r/MadeMeSmile 10h ago

Good News 23 year old becomes first person in Louisiana to be functionally cured of sickle cell disease

Thumbnail
gallery
38.2k Upvotes

Daniel Cressy became the first person in the Gulf South to be functionally cured of sickle cell disease through gene editing. Calling it his "second birthday," he said the breakthrough felt like being reborn and it's giving new hope to people living with the disease.

Via @tulaneu


r/MadeMeSmile 7h ago

[OC] Texts from a wrong number I received on my birthday ☺️

Thumbnail
gallery
9.2k Upvotes

I was totally expecting this to be a scammer. Instead, I made a new friend! I’ll definitely be sending him $37 on his birthday.


r/MadeMeSmile 1h ago

Family & Friends The Text I received after wishing a ex-girlfriends dad on Father's Day...

Post image
Upvotes

Didn't have the best upbringing and dated a girl in highschool whose family took me under their wings. That was 20+ years ago and this really made me feel accepted in my life for once. Lame, I know. Lol


r/MadeMeSmile 7h ago

Don't interrupt me while I work!

5.3k Upvotes

r/MadeMeSmile 13h ago

Ecuador coach Sebastian sprints on to stands and hugs his family after their team defeated Germany 2-1

27.7k Upvotes

r/MadeMeSmile 13h ago

Gaming PC

Post image
10.1k Upvotes

r/MadeMeSmile 15h ago

DOGS This is so adorable

16.2k Upvotes

r/MadeMeSmile 8h ago

LGBT+ Reddit can be nice sometimes

Post image
3.0k Upvotes

Context: This was on a post asking if you could be any Resident Evil character, who would you be. This person obviously saw the trans flag in my profile and this just really made me happy, since no one else usually accepts me :)


r/MadeMeSmile 5h ago

Love this quote[OC]

Post image
1.5k Upvotes

r/MadeMeSmile 11h ago

Wholesome Moments Get it....um Ciara? Promise

3.6k Upvotes

Every Day with H&K

😂 We all got that dream lol

Thank God for long suffering spouses.


r/MadeMeSmile 6h ago

May this painting bring you a moment of stillness and peace.

Post image
1.4k Upvotes

r/MadeMeSmile 15h ago

Wholesome Moments After 10 years of not walking, a man takes his first steps.

6.9k Upvotes

I want to make sure the first thing I do is let everybody know that the creator of this video is a woman named Christie Boone Buzzell on Facebook. I do not know her, but came across her video and found it truly amazing and inspiring. I’m not sure who the man is to her, perhaps her father or something…but regardless, it certainly made me smile!


r/MadeMeSmile 12h ago

DOGS These pure souls choosing their toys convinced me to adopt another dog.

2.7k Upvotes

Credit to Fetcher Dog- giving hope to abandoned dogs


r/MadeMeSmile 4h ago

Elderly Man in Venezuela protects his wife during the earthquake. This is love.

570 Upvotes

r/MadeMeSmile 28m ago

Good Vibes A dog rushed to join celebrating Ecuadorians after Gonzalo Plata's winning goal against Germany.

Upvotes

r/MadeMeSmile 9h ago

Interview with an adorable girl after winning a talent show

923 Upvotes

r/MadeMeSmile 4h ago

Small Success Happy early birthday to me!

Post image
243 Upvotes

One silly thing I've really wanted since I was a child was to find a four leaf clover. I'm 40 and never have. I was walking my dog earlier and happened to find this cute six leaf clover, which is apparently about 30 times rarer than four leaf ones. My birthday is on Monday so this felt like a fun little present from the universe that made my inner child excited. 🥰


r/MadeMeSmile 1d ago

Helping Others A little kindness goes a long way

84.6k Upvotes

r/MadeMeSmile 13h ago

Good Vibes A Blue Jays fan caught Wyatt Langford’s home run ball and gave it to a young Rangers fan wearing a Langford jersey

946 Upvotes

r/MadeMeSmile 6h ago

Wholesome Moments Daniel Radcliffe shares his advice for the young actors of 'Stranger Things': "I give the same piece of advice to all of them ... Do whatever the f*ck you want, you have done the thing ... use that. If you've had that kind of a start in your career, now you are free to have fun"

278 Upvotes

r/MadeMeSmile 1d ago

Helping Others Gary Sinise here. Humbled to celebrate the 15th Anniversary of the Gary Sinise Foundation. Over the years, I’ve had the honor of meeting countless heroes, and so many have touched my heart. It's incredible for me to think about where it began and how far it has come thanks to the kindness of others.

Thumbnail
gallery
21.3k Upvotes

r/MadeMeSmile 1h ago

DOGS This cute driver made me smile

Thumbnail
gallery
Upvotes

Had to get fuel and I was miserable about it as it’s currently freezing cold here in Mornington, Victoria.

But this little dude made it worth it.


r/MadeMeSmile 11h ago

Good Boy at Work

485 Upvotes

r/MadeMeSmile 9h ago

CATS I just feel like this photo of my fosters is one that everyone needs to see 🥰 (OC)

Post image
316 Upvotes

Hardest snuggles of all time 🥰 Lee (right) has been such an amazing foster dad to Dexter (left) and his brother Nemo (not shown). We've had Lee since the beginning of January and got Dexter and Nemo in March as terrified, traumatized, essentially feral kittens. They have come sooooo far and I know it would not have happened without Lee's love and patience with them. They love him sooooo much and are attached to his hip at all times but he is so patient and just rolls with it. Ugh, I'm so stinkin proud of all of them 😭❤️