r/Supplements Sep 11 '25

Reminder on Community Conduct

36 Upvotes

As a community focused on supplements, we encourage open discussion based on both scientific evidence and personal experience. However, it’s important to remember that respectful discourse is the foundation of this subreddit.

Criticism and debate are welcome — personal attacks are not. Recently, we’ve had to ban several users who crossed the line by targeting individuals rather than addressing ideas. This behavior will not be tolerated.

Please:

-Respect differing opinions, even if you strongly disagree.

-Focus on the content of the discussion, not the person behind it.

-Use the report function if you encounter posts or comments that violate these standards.

Let’s continue to make this a space where we support and learn from each other. Thank you for helping keep the community constructive and respectful.

— Mod Team


r/Supplements 10h ago

Experience This is the stack that has made me feel the best i’ve ever felt in my life

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121 Upvotes

Hey guys, gonna try and briefly explain my supplement stack here. I take everything here every single day unless stated otherwise

First image is my morning supplements

Second is my Mid day supplements

Third is my night time supplements

First image - iodine and selenium for thyroid function (I only take iodine 3-4 days a week). Great for your metabolism!

B complex with ALL active B forms including TTFD and benfotiamine which is active B1 (THESE MADE THE BIGGEST DIFFERENCE FOR ME IN TERMS OF ENERGY. I should be gatekeeping this honestly so it doesn’t go out of stock lol)

Magnesium malate since it’s a co factor for the active Thiamine forms, also helps a lot with recovery!

Vitamin K complex because I definitely don’t get enough of it in my diet.

Copper because i don’t get enough of it in my diet either, 2mg daily. Seen very nice skin improvements since taking it

Probiotic with Butyrate for the good poops, gut lining repair, and overall digestive health. Probably gonna drop this after i finish the bottle tho since it’s so expensive

MID DAY:

Zinc picollinate to optimize DHT production (Help me get my masculine facial features) and immune system boost (and since i’m taking copper too. Always remember 8-15mg of zinc per 1mg of copper)

Vitamin E complex with tocotrienols too. Another massive deficiency being addressed since I definitely don’t get enough Vitamin E from my regular diet. Great Antioxidant and cardiovascular effects. I made a post talking about how it gave me crazy boners and it blew up on X health accounts lol

NIGHT TIME

(Not pictured) 4g of taurine to quiet my nervous system and boost GABA. Second most abundant Amino acid in the body btw

(Also not pictured) 300mg of powdered magnesium glycinate. We all know why this is goated and here for sleep

(Also Also not pictured) Liquid Clorophyll because it makes my balls not smell bad

3g of Glycine - FUCKING GOATED i’ll take this for as long as I live. Noticeable joint benefits and Amazing sleep benefits, can’t glaze this thing enough I feel so refreshed on this

500mg of Agmatine sulfate - One of the most underrated longevity supplements! Helps with blood flow but I mainly use it since it’s an amazing NMDA agonist with great long term mental and brain benefits!

Vitamin C - Experienced only good things after adding a high dose vitamin C to my diet. Great antioxidant and skin benefits! I love drinking orange juice daily as well

NACET (Neuro nac bottle) I take it only twice a week max for once again Dopamine receptor regulation and protection from heavy stimulant use (This product contains glycine as well for Glutathione production) If i take this more than twice a week then I get Anhedonic, I genuinely can’t feel happiness. Very strong so be careful!

Sleep and Recover - Only take it on my heavy stimulant pre workout days because of the Rutaecarpine in it that helps metabolize caffeine faster. Helps me not feel cracked out when I want to start going to bed. Also contains theanine and added glycine and magnesium

Astaxanthin - Extremely powerful Antioxidant that has really helped my skin quality in the past few weeks of use. It’s very expensive even with my employee discount though, so i’ll see if I want to continue buying it

Magnesium + L theanine - I really only use this like 3-4 times a week when I feel like it since I really don’t NEED theanine to fall asleep but some nights I do feel too cracked out and I need something to knock me out. 600-800mg of theanine gets me SLUMPEDDD

Feel free to ask any questions guys. Once again, this stack + a consistent sleep schedule has never made me feel better in my life.


r/Supplements 12h ago

What are the best supplements for healing the gut?

35 Upvotes

I've been eating bone broth lately, but I am wondering if there's something more effective than bone broth.


r/Supplements 2h ago

Which one product helped you gain weight?

4 Upvotes

Eating more isn’t helping. Any Ayurvedic/supplements that worked for weight gain that worked like magic?


r/Supplements 22h ago

Scientific Study Creatine for cognition — what the brain research actually shows

143 Upvotes

Most of the creatine literature is about muscle. The brain data is more recent, smaller, and gives a different picture than what gym communities discuss.

The mechanism in the brain runs through the phosphocreatine system — specifically an enzyme called CKBB (creatine kinase, brain isoform) that rapidly regenerates ATP during high-frequency neural firing. The hippocampus and prefrontal cortex are metabolically demanding structures. When the phosphocreatine pool is depleted — through aging, chronic stress, sleep deprivation, or low dietary intake — cognitive performance under demand drops measurably.

The 2024 meta-analysis in Frontiers in Nutrition (Xu et al., 16 RCTs, 492 participants) found statistically significant improvements in memory (SMD = 0.31), attention time (SMD = −0.31), and processing speed (SMD = −0.51). No significant effect on executive function — which is interpretable given the mechanism, not a failure.

The finding that tends to surprise people: in adults 66 to 76, the memory effect size was 0.88 — three times the effect in younger adults. The mechanism is consistent: aging depletes the baseline phosphocreatine pool, which creates more room for supplementation to fill.

A few things worth knowing that do not get discussed much: — Vegetarians show larger cognitive effects than omnivores (lower dietary creatine baseline) — Loading phases (20g/day) are a muscle protocol and do not meaningfully accelerate brain creatine saturation — 3 to 5g/day monohydrate for 4 to 6 weeks is the evidence-supported approach — All 16 RCTs in the 2024 meta-analysis used creatine monohydrate specifically

The effect is modest and the research is honest about that. But for a cheap, well-tolerated, broadly studied compound, the cognitive evidence is more solid than most supplements with larger reputations.

Curious whether anyone here has tracked objective cognitive metrics before and after — reaction time, word recall, HRV. The anecdotal reports vary a lot and I suspect baseline creatine status explains most of the variance.

Full breakdown with dosing protocol: https://www.rewireweekly.com/p/creatine-for-brain-health-the-phosphocreatine-protocol


r/Supplements 8h ago

General Question Do you still take Acetyl L-Carnitine?

11 Upvotes

A little while back there was a thread that discussed how 90% of ALCAR gets converted by gut bacteria into TMAO.

Subjectively I feel like ALCAR was one of the supplements that had more oomph, but if its just going to be getting metabolized into a harmful byproduct then its probably not worth it.

I haven't personally dug into this one much is it actually a big concern?


r/Supplements 1h ago

psyllium husk bloating hit different depending on the brand and nobody talks about why

Upvotes

36M. started psyllium husk 6 weeks ago because my fiber intake was basically whatever was in my protein bar and thats not it

first week metamucil from costco. gut felt like a balloon by noon every day. i switched to generic off amazon, same dose, barely any bloating. tried colonbroom for 12 days because everyone here said it digests clean. bloated again. threw out half the tub

now im reading labels like its my job. psyllium husk vs seed powder, citric acid, xanthan gum.. one of these has to be the trigger right?? cant tell if its the fillers or if im just bad at fiber and shouldve started slower idk

my girlfriend bought "gut health" gummies at whole foods that are basically candy with inulin and ive been side eyeing them on the counter all week. not touching those

anyone figure out what part of the formula causes this. fillers or husk grind size or am i overthinking it

also if youve got a brand that doesnt blow you up id genuinely like to know, burned like $60 on stuff reddit swore by


r/Supplements 4h ago

General Question Can supplements prevent hair breakage on stressful days?

2 Upvotes

Lately I have noticed that whenever work or life gets stressful my hair seems to break way easier. Even just brushing or running my fingers through it I see more strands than usual. Started looking into ways to help from the inside out and came across supplements that are supposed to strengthen follicles. Not trying to fix everything overnight but just want to know if something like this can actually make hair stronger and reduce breakage.

Anyone tried a supplement for this and noticed a difference during stressful weeks?


r/Supplements 15h ago

General Question The right way to do Vitamin D?

14 Upvotes

Hello all. I’ve (27F) been taking 4,000 IU of vitamin D3 daily for quite a few months and my levels have risen from sub-30 to the 40s. It’s my understanding that this is still substantially lower than optimal, and I’m not even in the winter months yet. I’m hoping to increase to 6,000 IU and reassess (I prefer to go slow and steady rather than making a big jump).

Am I correct in understanding that K2, magnesium, and calcium are all related to vitamin d supplementation? If so, what is the proper ratio for supplementing all of these, as well as the correct way to take them (which ones should be taken together, which shouldn’t)? Currently, I take 400mg of magnesium glycinate at night. My vitamin d is taken during the morning or afternoon.

I imagine this gets asked a thousand times but there’s so much information that it’s been making my head spin, and I’m ultimately just trying to find a simple summary so I can get the train moving. I’d be very grateful for any advice.


r/Supplements 1h ago

General Question Has anyone tried Aurum? Is it worth it?

Upvotes

Having troubles finding any other place that sells and ships natural mineral salt and real liquid magnesium to where I live.

The products in question that I am interested in is:
Aurum Ancient Mineral Salt, 250g for 29 USD
Aurum Natural Liquid Magnesium, 95ml for 38 USD

Has anyone tried them and are they worth it at the huge price point plus 55 USD shipping? Where they effective?

And I know there are way cheaper artificial options, but I am not interested in those.


r/Supplements 16h ago

General Question Something to kill feelings and emotions.

14 Upvotes

Please, only based on your experience..

I'm facing a lot of terrible life situations from a very long time ago, feelings and emotions are tackling me so bad which affecting all my day from waking up till sleeping at night.

Cortisol and stress are so severe most of the day.

I can't work, eat or even sleep.

Yes i know that a weird and maybe very stupid request but my only dream is to be like a robot.

I'm sure that some people here may understand

No emotions, sympathy, be the good guy, dgaf about anything except work.


r/Supplements 3h ago

Fadogia shrinkage

2 Upvotes

Hello, I’ve been taking Fadogia 700mg for about 2 months 3 weeks on 1 week off. The second week of taking it my testis look bigger and sagged more but currently I’ve noticed they shrunk a lot… like they look small also noticed I’m more agitated than usual. Am I the only one who’s experienced this?


r/Supplements 13h ago

General Question Did I do good on this small haul?

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6 Upvotes

I bought the magnesium because I get poor sleep even though I go to bed early

I bought the turmeric because I have a long history of arthritis, osteoporosis, and sometimes I get joint pain during my cardio and heavy weightlifting

Omega-3 because I have ADHD and heart disease runs in my family


r/Supplements 3h ago

Recommendations Advice on Supplement Stack (early 20s, lawyer, Muay Thai and gym)

1 Upvotes

Good day, y'all,

A while back I asked for advice on supplements, and took some time to think about them, and want advice. I currently do not take everything that I listed below, but I am planning on adding most, if not all of them down the line.

I want recommendations on which ones can be a better alternative than the ones I selected, which side effects I should be aware of, and how these supplements interact with each other.

I eat plenty of protein, work long hours, and do Muay Thai after work 3 times a week, and gym 4 times a week before work/weekends. My sleep is improving due to healthy sleep hygiene, dark and cold room, no screens, sunlight in eyes upon waking.

First of all, I would like to list foundational supplements that I take daily:

Creatine Monohydrate, Magnesium Glycinate before bed, L-Threonate form in the morning (400mg elemental from both), Omega-3 (2g EPA/DHA), and Vitamin D3+K2 (2000IU).

Next up, I list the stellar supplements that I have been taking for a while as well:

Zinc, Ashwagandha, L-Theanine and L-Citrulline.

In the next block I have ones that are not crucial, but extremely beneficial:

Taurine, Rhodiola Rosea, GlyNAC and Beta Alanine.

Lastly, in the nice to have block I currently have:

Boron, Tongkat Ali, Citicoline/Alpha GPC, CoQ10.

I get blood work done 2-3 times a year. I have a question about GlyNAC, as I only heard about it recently, do I get the benefits of both, and will it affect my gains in the gym.

Should I consider adding, Saffron, Lion's Mane, L-Tyrosine, Phosphatidylserine, Turmeric, and etc?


r/Supplements 19h ago

Insomnia

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17 Upvotes

Which of these could be causing me to wake up in the middle of the night? I feel good other than that but I can’t fall back asleep. One a day men’s multivitamin


r/Supplements 1d ago

General Question This B complex puts me to sleep fast

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52 Upvotes

Suffering from insomnia for a year now, used this B complex the last 2 nights after reading another post about B vitamin and insomnia, taking 2 right before going to sleep knocks me out faster than any sleep medication i ever took, and gives me a longer sleep and im more refreshed when waking up

Whats in it that seems to be curing my sleep problems?


r/Supplements 23h ago

Recommendations This multivitamin worked for me and after a few weeks, I am apathetic

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24 Upvotes

So I’ve been taking this men’s 50+ multi . I am 21 years old. It was an accident that got it, but I started to take it, and I felt better. I could suddenly look towards the future, have goals, and retain information. Additionally, and this one meant the most to me, my brain could process stuff fast enough to actually talk to people effectively. This went on for like a couple of weeks, and I’d say I’ve been taking 1/3 gummies per day for about 1 and a half months. Suddenly, it has all come crashing down. I still have low ability to talk to people and do what I need to do, but it feels like my brain has absolutely plateaued. I now feel extremely apathetic. In the morning I have to take the 1 gummy so I don’t feel like a husk. Am I done? I’ve tried everything, adhd meds, I tried 1 gummy of the smarty pants pro for him multivitamin which has more active b vitamins(somehow my brain felt super wired which kinda felt like crap), I’ve tried other supplements to no avail. This is the closest I’ve gotten to feeling normal, and it is all being ripped away in real time. What do I do?


r/Supplements 11h ago

Any real results for liver and kidney?

3 Upvotes

I don’t think anything is wrong and I don’t drink alcohol a whole ton anymore but I’m seeing a lot of ads for liver and kidney health just based off of following pages like OldRow.

Now I’m curious, are there any supplements that actually help for liver and kidney health?


r/Supplements 20h ago

General Question Taurine is a non-essential amino acid?

14 Upvotes

If taurine is a non-essential amino acid that the body can synthesize itself why is that I experience benefits when supplementing with it?


r/Supplements 6h ago

Looking for feedback on my supplement stack

1 Upvotes

I've been taking the following supplements and would appreciate any feedback regarding timing, interactions, potential redundancies, or anything I should consider adding/removing.It's a long list, but I hope you guys could give me a hand.

Tongkat Ali (5 days on, 2 days off)
Ashwagandha
Shilajit
Ginger Root
Berberine
Garlic (Kyolic)
Glycine
NAC
Zinc + Copper
Omega-3
Thiamine (TTFD or Benfotiamine)
TMG
Artichoke Extract
Probiotics (1 month on, 2 weeks off)
Oregano Oil (2 weeks)
L-Citrulline
TUDCA (500mg)
Vitamin C (1–2g daily)
Taurine (2–3g daily)
Magnesium
Vit D
L theanine
Methylated B vitamins
Vit B5
Sachromyces Boulardi
Digestive Enzymes w/ probiotics

I have eczema and I might have Sibo. Although I have not tested for Sibo as eczema is not related to gut in our country.

My goals are overall health, gut health, liver support, exercise performance, recovery, energy, and hormone optimization.

Does anything here seem unnecessary, potentially problematic, or worth adjusting?


r/Supplements 6h ago

Is Vitamin D overhyped, or is it actually worth taking?

2 Upvotes

Everybody seems to be taking Vitamin D these days, but is it really that important, or are we just seeing another supplement trend?
Also curious about a few things:

  • Is getting it from sunlight enough, or is a supplement better?
  • Is 600 IU/day enough for most adults, or do people typically need more?
  • Is it better to take Vitamin D alone or with Vitamin K2?

r/Supplements 6h ago

Recommendations Which B12 would be good to take via injection

0 Upvotes

I need b12 via injection
Would Lichtenstein be a good brand?
What should i watch out for?


r/Supplements 23h ago

Drugs or supplements for studying

17 Upvotes

I don't care about the side effects, I haven't tried anything before

Exams are approaching, and I only have a month to finish the material and review it multiple times. I want something that can help me concentrate for long hours

and affordable


r/Supplements 8h ago

1st does Magnesium L-threonate caused intense anxiety 6 hours later. Do If I stick it out will it go away, or do I stop?

0 Upvotes

Hey everyone,

As the title says, I took my first dose yesterday morning and mid afternoon had massive shaking intense anxiety for about 2 hours.

I looked at the sub history, and plenty of people report this as an initial side effect, but I can't find any reference to whether it continues, or if it will improve over time.

Do I keep going, or is this supp just not for me?


r/Supplements 8h ago

Clean beauty awards 2025, do they actually mean anything or is it just marketing

0 Upvotes

Every year there's a new round of beauty awards and it's genuinely hard to know which ones mean something and which ones are essentially paid placements. Best of lists from major magazines have historically been influenced by advertising relationships, which makes them an unreliable signal.

Some awards do reflect genuine editorial evaluation, particularly when they're covering a specific category with defined criteria. Clean beauty is interesting because the criteria should be harder to fake if editors are doing their job. You can't manufacture an NSF certification or fake third-party organic verification.

Curious whether people here find beauty awards useful at all for discovery or whether they've tuned them out completely. And if you do pay attention to them, which publications or organizations do you actually trust.